I discovered orienteering too late in college to do this, but I think getting the residence halls is another good angle for orienteering. How many students at these universities live on campus, and what is the atmosphere like (eg: are there dorm events, socials, etc)?
I went to the University of Kansas and I lived in the dorms for 3 years and I was involved in my dorm's "government" which was basically an event planning group. I think orienteering would be a great fit for a dorm activity because:
-- It involves getting acquainted with the university, both in an orientation sense (which building is which?), but also with some history (lots of old plaques and sculptures, etc).
-- The students are already living there, so they don't have to travel far.
-- It's exercise
-- It's a good way to bond with roommates and hallmates (team up!)
-- You can have a competition amongst rooms, floors, dorms, etc.
-- Residence halls are always looking for more events to get residents involved.
-- Residents are always looking for fun and cheap things to do.
The Choose Your Adventure format would work best, at least to start, because it's the most flexible for a wide range of interests and abilities, plus it has a mass start and finish, so you could combo with say a dinner or something else.