I tend to run home one day and then run in the next morning so that I can just leave my clothes and winter boots and jacket and stuff (I bring extra underwear...) and have much less to bring the next day. I suppose that the computer is the worst part for you, though, so if you can't leave that then eh.
Yeah, thought about that. There's a lot of planning involved, though, to figure all that out. And I'm only in Chicago for a few weeks so I have but a subset of clothes, etc.
Anyway, the project for which I needed my own computer may soon be over, which would allow me to cut down on the weight, somewhat.