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Discussion: Smell

in: blairtrewin; blairtrewin > 2020-03-24

Mar 24, 2020 10:49 PM # 
TheInvisibleLog:
Have been informed no cohort studies reporting this, and there have been quite a few studies in China. So probably evidence status at this stage - anecdotal.
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Mar 25, 2020 12:34 AM # 
tRicky:
Maybe it's hard for the infected to smell anything through a mask so they take it as a symptom.
Mar 25, 2020 2:21 AM # 
TheInvisibleLog:
I thought it was the clogged up sinuses.
Mar 27, 2020 11:00 PM # 
jennycas:
I'm trying to work out whether it's anything to do with angiotensin-converting enzyme; there's been a flurry of media around the fact that CV enters cells via ACE-2, and that people on ACE-inhibitor medication (for heart/blood pressure) might be more susceptible to CV's effects on the lungs (because apparently inhibiting conversion from angiotensin I to angiotensin II might mean that the ACE-2 receptors are then upregulated and it's easier for the virus to get into the lungs...anyway, that's not been definitively proven.

What intrigued me is that one of the side effects of ACE-inhibitor type medications can be loss of smell/taste, so I am trying to work out if this could have any relevance to the purported loss of smell allegedly related to CV. But hey, what would I know, I'm not a pharmacologist!

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